Ritsumeikan University Syllabus

Course Name	Year	Term	Period	Faculty / Graduate School	All Instructors	Credits
81788:[2025 Spring]Cost-effectiveness Evaluation Exercise1 (A)	2025	Spring	Mon2	Graduate　School　of　Life　Sciences	KASHIWA MUNENOBU、SHIMOZUMA KOJIRO、SUZUKAMO YOSHIMI、MORIWAKI KENSUKE	2

Campus

BKC

Class Venue

BKC

Language

Japanese

Course Outline and Method

費用対効果評価を含む医療技術評価は、医療資源の公平・効率的な配分のための意思決定支援を目的とした学際的な研究領域であり、臨床疫学、医療統計学、医療経済学、リアルワールドデータ分析、健康関連QOL評価など多様な専門分野の連携・協働が前提となる。本講義では、医療技術評価分野の専門人材として必要となる実務的な知識・技能の習得を目標とする。

各講義前後の一定期間、講義に関する教材をmanaba+R上に提示する。課題や小レポートについても一定期間manaba+R上に提示するとともに、その期間内に回収する。

★決められた期間を過ぎてからの課題レポートの提出はいかなる理由があっても認めない。

授業形態：オンライン

Health technology assessment, including cost-effectiveness evaluation, is an interdisciplinary research field that aims to support decision-making for the fair and efficient allocation of healthcare resources, and it is premised on collaboration and cooperation between various specialist fields, including clinical epidemiology, medical statistics, health economics, real-world data analysis, and health-related quality of life evaluation. The aim is to acquire the practical knowledge and skills needed as a specialist in the field of health technology assessment.

The course materials will be posted on manaba+R for a certain period before and after each lecture. Assignments and short reports will also be posted on manaba+R for a certain period, and will be collected within that period.

★Assignments and reports submitted after the specified period will not be accepted for any reason.

Class format: Online

Student Attainment Objectives

1. 新規医療技術の基本情報を収集・整理した上で、ステークホルダーに伝達することができる。
2. 診療実態や異質性を考慮した上で、適切な分析の枠組みを提案することができる。
3. システマティックレビューを実施し、臨床エビデンスの収集・要約ができる。
4. 臨床試験の批判的吟味や各種の統計解析を実施し、追加的有用性の評価を行うことができる。
5. 費用効果分析モデルの構造、パラメータ設定を理解した上で、ステークホルダーに伝達することができる。
6. 費用効果分析の再分析方針を立案し、実践することができる。
7. 再分析の結果を所定の様式に沿って報告することができる。

1. After collecting and organizing basic information on new health technologies, you can communicate it to stakeholders.
2. You can propose an appropriate analytical framework, taking into account the clinical practice and heterogeneity.
3. You can conduct a systematic review and collect and summarize clinical evidence.
4. Can conduct critical appraisal of clinical trials and various statistical analyses to evaluate additional benefits.
5. Can understand the structure and parameter settings of cost-effectiveness analysis models and communicate them to stakeholders.
6. Can develop and implement a policy for reanalysis of cost-effectiveness analysis.
7. Can report the results of reanalysis in a prescribed format.

Recommended Preparatory Course

応用生命医科学特論
Applied biomedical science

Course Schedule

Lecture/Instructor（When there are multiple instructors)	Theme
Lecture/Instructor（When there are multiple instructors)	Keyword, References and Supplementary Information
	本科目は+R授業対象科目。第1回に+R授業を実施。詳細はmanaba+Rを参照/This class includes +R-Jugyo. +R-Jugyo is conducted in the 1st session. For the details, refer to manaba +R. イントロダクション/Introduction
	ビデオ　20min/VOD 20min
1	基本情報の調査1 Basic Information Survey 1
1	疫学情報、位置づけ・特性、標準治療などの詳細、作用機序メカニズムの詳細 Epidemiological information, positioning and characteristics, details of standard treatment, etc., details of mechanism of action
2	基本情報の調査2 Basic Information Survey 2
2	有効性、安全性、健康関連QOLなど臨床的エビデンス Clinical evidence, such as efficacy, safety, and health-related QOL
3	基本情報の調査3 Basic Information Survey 3
3	諸外国のHTA機関における評価結果や分析手法の概要、費用対効果評価の文献情報とその概要 Overview of evaluation results and analysis methods at HTA agencies in other countries, literature information and overview of cost-effectiveness evaluation
4	分析枠組みの設定1 Analysis Framework Setting 1
4	分析対象集団の検討（治療効果の異質性などの考慮） Consideration of the target population for analysis (consideration of factors such as heterogeneity of treatment effects)
5	分析枠組みの設定2 Analysis Framework Setting 2
5	比較対照技術の検討（診療実態、相対的効果や費用対効果などの考慮） Consideration of the comparative technology (consideration of factors such as actual clinical practice, relative effectiveness and cost-effectiveness)
6	追加的有用性の評価1 Evaluation of additional benefits 1
6	システマティックレビューの実施 Implementation of systematic review
7	追加的有用性の評価2 Evaluation of additional benefits 2
7	臨床エビデンスの批判的吟味 Critical appraisal of clinical evidence
8	追加的有用性の評価3 Evaluation of additional benefits 3
8	統合解析や間接比較の検討 Consideration of integrated analysis and indirect comparisons
9	費用対効果の評価1 Cost-effectiveness evaluation 1
9	先行研究などを参考にしたモデル構造の検討 Consideration of model structure based on previous studies, etc.
10	費用対効果の評価2 Cost-effectiveness evaluation 2
10	先行研究などを参考にしたパラメータ推定法の検討 Consideration of parameter estimation method based on previous studies, etc.
11	企業分析のレビュー1 Review of company analysis 1
11	ガイドライン準拠の確認、諸外国HTA機関の評価結果の確認 Confirmation of compliance with guidelines, confirmation of evaluation results of HTA agencies in other countries
12	企業分析のレビュー2 Review of company analysis 2
12	企業分析の妥当性の検討、専門家意見の聴取 Examination of the validity of the company analysis, hearing of expert opinions
13	再分析の実施1 Reanalysis 1
13	追加的有用性評価の再分析 Reanalysis of additional benefit evaluation
14	再分析の実施2 Reanalysis 2
14	費用対効果評価の再分析 Reanalysis of cost-effectiveness evaluation

Class Format

オンライン
Online

Recommendations for Private Study

新聞やweb news、学術論文等で発信される、新しい医療技術の有効性、安全性、費用対効果の評価について、常にアンテナを張っておく必要がある。

It is necessary to keep a close eye on the evaluation of the efficacy, safety and cost-effectiveness of new health technologies as they are disseminated in newspapers, web news and academic papers.

Grade Evaluation Method

Kind	Percentage	Grading Criteria etc.
Final Examination (Written)	0
Report Examination (A report to be submitted by the unified deadline)	0
Exams and/or Reports other than those stated above, and Continuous Assessment　 (Evaluation of Everyday Performance in Class)	100	出席状況とレポートを総合的に評価する。 sum of the attendance score and the report score

Grade Evaluation Method （Note）

Advice to Students on Study and Research Methods

Prior approval to participate in the HTA (Health Technology Assessment) Educational Program is required to enroll in this course.

Textbooks

Textbooks （Frequency of Use, Note）

Reference Books

Reference Books （Frequency of Use, Note）

Web Pages for Reference

How to Communicate with the Instructor In and Out of Class(Including Instructor Contact Information)

Other Comments

【科目ナンバリング・カリキュラムマップはこちらから/Click here to see the Curriculum-Map and Course-Numbering】
URL:https://secure.ritsumei.ac.jp/students/pathways-future/course/curriculum.html/